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Biogenesis of poxviruses: preliminary characterization of conditional lethal mutants of vaccinia virus defective in DNA synthesis.

作者信息

McFadden G, Dales S

出版信息

Virology. 1980 May;103(1):68-79. doi: 10.1016/0042-6822(80)90126-9.

DOI:10.1016/0042-6822(80)90126-9
PMID:6245533
Abstract
摘要

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Biogenesis of poxviruses: preliminary characterization of conditional lethal mutants of vaccinia virus defective in DNA synthesis.痘病毒的生物发生:DNA合成缺陷的痘苗病毒条件致死突变体的初步特征分析。
Virology. 1980 May;103(1):68-79. doi: 10.1016/0042-6822(80)90126-9.
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Identification of temperature-sensitive mutants of vaccinia virus that are defective in conversion of concatemeric replicative intermediates to the mature linear DNA genome.痘苗病毒温度敏感突变体的鉴定,这些突变体在将串联复制中间体转化为成熟线性DNA基因组方面存在缺陷。
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Acta Virol. 1978 Mar;22(2):81-90.

引用本文的文献

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Clustered charge-to-alanine mutagenesis of the vaccinia virus A20 gene: temperature-sensitive mutants have a DNA-minus phenotype and are defective in the production of processive DNA polymerase activity.痘苗病毒A20基因的成簇电荷至丙氨酸诱变:温度敏感突变体具有DNA缺失表型,且在进行性DNA聚合酶活性的产生方面存在缺陷。
J Virol. 2001 Dec;75(24):12308-18. doi: 10.1128/JVI.75.24.12308-12318.2001.
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Construction of a vaccinia virus deficient in the essential DNA repair enzyme uracil DNA glycosylase by a complementing cell line.
通过互补细胞系构建缺乏必需DNA修复酶尿嘧啶DNA糖基化酶的痘苗病毒。
J Virol. 1997 Jul;71(7):4997-5002. doi: 10.1128/JVI.71.7.4997-5002.1997.
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Mutations in active-site residues of the uracil-DNA glycosylase encoded by vaccinia virus are incompatible with virus viability.牛痘病毒编码的尿嘧啶-DNA糖基化酶活性位点残基的突变与病毒生存能力不兼容。
J Virol. 1996 Nov;70(11):7965-73. doi: 10.1128/JVI.70.11.7965-7973.1996.
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Human cytomegalovirus uracil DNA glycosylase is required for the normal temporal regulation of both DNA synthesis and viral replication.人巨细胞病毒尿嘧啶DNA糖基化酶对于DNA合成和病毒复制的正常时间调控是必需的。
J Virol. 1996 May;70(5):3018-25. doi: 10.1128/JVI.70.5.3018-3025.1996.
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A poxvirus-encoded uracil DNA glycosylase is essential for virus viability.一种痘病毒编码的尿嘧啶DNA糖基化酶对病毒的生存能力至关重要。
J Virol. 1993 May;67(5):2503-12. doi: 10.1128/JVI.67.5.2503-2512.1993.
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Identification of a poxvirus gene encoding a uracil DNA glycosylase.一种编码尿嘧啶DNA糖基化酶的痘病毒基因的鉴定。
Proc Natl Acad Sci U S A. 1993 May 15;90(10):4518-22. doi: 10.1073/pnas.90.10.4518.
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The vaccinia virus D5 protein, which is required for DNA replication, is a nucleic acid-independent nucleoside triphosphatase.痘苗病毒D5蛋白是DNA复制所必需的,它是一种不依赖核酸的核苷三磷酸酶。
J Virol. 1995 Sep;69(9):5353-61. doi: 10.1128/JVI.69.9.5353-5361.1995.
9
Isolation and genetic characterization of temperature-sensitive mutants of vaccinia virus WR.痘苗病毒WR温度敏感突变体的分离与遗传特征分析
J Virol. 1982 Sep;43(3):778-90. doi: 10.1128/JVI.43.3.778-790.1982.
10
Biochemical and genetic characterization of vaccinia virus temperature-sensitive mutants with DNA- and DNAf-phenotypes.具有DNA和DNAf表型的痘苗病毒温度敏感突变体的生化与遗传学特征分析
Arch Virol. 1983;77(2-4):209-21. doi: 10.1007/BF01309268.