[体外电刺激对大鼠脑突触体超微结构及功能的影响]
[Ultrastructural and functional changes in the synaptosomes of the rat brain on in vitro electrostimulation].
作者信息
Rodina V I, Salata L K, Rozhanets V V, Pozdniakov O M, Glebov R N
出版信息
Biull Eksp Biol Med. 1980 Feb;89(2):143-5.
PMID:6245740
Abstract
Electrostimulation of suspension of the rat brain synaptosomes causes Ca(2)+-dependent endogenous norepinephrine release and at the same time Ca(2)-dependent increase of the mediator content in the synaptosomes. The activity of cAMP declines under the same conditions. Electrostimulation does not alter the ultrastructure of the synaptosomes but raises the content of high electron density synaptosomes.
摘要
对大鼠脑突触体悬浮液进行电刺激会导致钙离子依赖的内源性去甲肾上腺素释放，同时也会使突触体内介质含量出现钙离子依赖的增加。在相同条件下，环磷酸腺苷（cAMP）的活性会下降。电刺激不会改变突触体的超微结构，但会增加高电子密度突触体的含量。
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