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申克孢子丝菌分生孢子合成单鼠李糖基L-鼠李糖-D-甘露聚糖

Synthesis of monorhamnosyl L-rhamno-D-mannans by conidia of Sporothrix schenckii.

作者信息

Travassos L R, Mendonça-Previato L

出版信息

Infect Immun. 1978 Jan;19(1):1-4. doi: 10.1128/iai.19.1.1-4.1978.

Abstract

A rhamnomannan containing single-unit alpha-L-rhamnopyranose side chains was identified in isolated conidia from Sporothrix schenckii. Such a rhamnomannan differed from the dirhamnosyl rhamnomannan synthesized by the hyphae but was very similar to the monorhamnosyl rhamnomannan formed in yeastlike cells. Nuclear magnetic resonance spectroscopy and chemical analysis were used to compare these polysaccharides. Based on the distribution of different rhamnomannans in different S. schenckii cell types and in view of the reactivity of some human antisera previously reported (6), the formation of hyphae in vivo is suggested.

摘要

在申克孢子丝菌分离的分生孢子中鉴定出一种含有单单元α-L-鼠李吡喃糖侧链的鼠李甘露聚糖。这种鼠李甘露聚糖与菌丝合成的二鼠李糖基鼠李甘露聚糖不同,但与酵母样细胞中形成的单鼠李糖基鼠李甘露聚糖非常相似。利用核磁共振光谱和化学分析来比较这些多糖。基于不同鼠李甘露聚糖在不同申克孢子丝菌细胞类型中的分布,并考虑到先前报道的一些人抗血清的反应性(6),提示在体内形成菌丝。

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