Streuli H K, Fartab M, Radlowsky O, Dippon R
Helv Chir Acta. 1978 Jan;44(5-6):611-21.
Breast carcinoma is the most frequent form of cancer in women. In Switzerland 1265 women died of it in 1975, the mortality rate is rising slowly, the cause of this fact being unclear. There is no uniformity about the best treatment of breast cancer. We analyzed 454 carcinomas, operated in the years 1961--1971 after Halsted, Patey and McWhirter. We found similar 5- and 10-year survival rates with the Halsted and the Patey method of operation, however, decidedly worse results with the simple mastectomy. Nowadays we recommend the modified radical excision of the breast after Patey at all stages; in addition we treat all patients with postoperative X-ray therapy or prescribe an adjuvant cytostatic therapy based on the experimental study of the SAKK (Swiss Therapy Group for Clinical Cancer Research).
乳腺癌是女性中最常见的癌症形式。1975年在瑞士有1265名女性死于乳腺癌，死亡率正在缓慢上升，这一事实的原因尚不清楚。对于乳腺癌的最佳治疗方法尚无统一意见。我们分析了1961年至1971年间按照霍尔斯特德、佩蒂和麦克惠特方法进行手术的454例癌症病例。我们发现，采用霍尔斯特德和佩蒂手术方法的5年和10年生存率相似，然而，单纯乳房切除术的结果明显更差。如今，我们建议在所有阶段都采用佩蒂改良根治性乳房切除术；此外，我们对所有患者进行术后放疗，或根据瑞士临床癌症研究治疗组（SAKK）的实验研究开辅助性细胞抑制疗法。
