Checkley S A
Psychol Med. 1980 Feb;10(1):35-53. doi: 10.1017/s0033291700039593.
Neuroendocrine tests are now available for studying monoamine function in the brains of patients with mental illness. Great care is required in the selection of drugs which act upon specific monoamine receptors to produce specific hormonal responses. Equal care is required in the control of biological variables which may influence hormonal release. Recently reported neuroendocrine studies of depressive illness are assessed in these terms. The results of these studies support the hypothesis that there is defective noradrenergic function in the brains of some patients with depressive illness.
神经内分泌测试现在可用于研究精神疾病患者大脑中的单胺功能。在选择作用于特定单胺受体以产生特定激素反应的药物时需要格外小心。在控制可能影响激素释放的生物学变量方面也需要同样谨慎。本文从这些方面对最近报道的抑郁症神经内分泌研究进行了评估。这些研究结果支持了这样一种假说，即一些抑郁症患者大脑中存在去甲肾上腺素能功能缺陷。
