Department of Cardiology, Dunedin School of Medicine, Dunedin Public Hospital, University of Otago, Dunedin 9001, New Zealand.
J Geriatr Cardiol. 2011 Jun;8(2):121-6. doi: 10.3724/SP.J.1263.2011.00121.
Depression is a common medical problem and is more prevalent among patients with coronary artery disease. Whether early detection and treatment of depression will enhance cardiovascular outcome is uncertain. Obviously, the safety and efficacy of the anti-depression drugs is an important link. This article reviews the patho-physiologic and behavioural links between depression and cardiovascular disease progression, the treatment of depression, and the potential benefits of anti-depressants in patients with coronary disease.
抑郁症是一种常见的医学问题,在冠心病患者中更为普遍。早期检测和治疗抑郁症是否会改善心血管结局尚不确定。显然,抗抑郁药物的安全性和疗效是一个重要环节。本文综述了抑郁症与心血管疾病进展、抑郁症治疗以及抗抑郁药在冠心病患者中的潜在益处之间的病理生理和行为联系。