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手臂内外侧痣细胞痣的患病率。

Prevalence of nevocytic nevi on lateral and medial aspects of arms.

作者信息

Kopf A W, Lazar M, Bart R S, Dubin N, Bromberg J

出版信息

J Dermatol Surg Oncol. 1978 Feb;4(2):153-8. doi: 10.1111/j.1524-4725.1978.tb00398.x.

DOI:10.1111/j.1524-4725.1978.tb00398.x
PMID:624799
Abstract

The numbers of clinically diagnosed, elevated nevocytic nevi (at least 2 mm in diameter) within 50 sq cm areas on the lateral and medial aspects of the arms of 1,000 subjects (age range 2 to 87 years) were compared. A total of 349 nevi was found on the lateral aspects and only 116 on the medial aspects of arms. Nevi were found on the lateral aspects of the arms in 23.4% (234) of the subjects and on the medial aspects in but 10.9% (109) of the subjects. These differences are highly significant in both men and women. Nevi were found in 30.2% (281) of the 930 whites but in only 9.1% (5) of the 55 blacks included in the study. Also, blacks did not show greater prevalence of nevi on the lateral as compared to the medial aspects of their arms. One explanation for the greater prevalence of nevi on the lateral over that on the medial aspects of the arms is that sunlight plays a role in the induction of acquired nevocytic nevi.

摘要

比较了1000名受试者(年龄范围为2至87岁)手臂内外侧50平方厘米区域内临床诊断为增大的痣细胞痣(直径至少2毫米)的数量。在手臂外侧共发现349颗痣,而在内侧仅发现116颗。23.4%(234名)受试者的手臂外侧有痣,而只有10.9%(109名)受试者的手臂内侧有痣。这些差异在男性和女性中均极为显著。在该研究纳入的930名白人中,30.2%(281名)有痣,而55名黑人中只有9.1%(5名)有痣。此外,黑人手臂外侧的痣患病率并未高于内侧。手臂外侧痣的患病率高于内侧的一种解释是,阳光在后天性痣细胞痣的诱发中起作用。

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引用本文的文献

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Associations of pigmentary and naevus phenotype with melanoma risk in two populations with comparable ancestry but contrasting levels of ambient sun exposure.在具有相似遗传背景但环境阳光暴露水平不同的两个人群中,色素和痣表型与黑色素瘤风险的关联。
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Malignant melanoma in a black child: predisposing precursors and management.一名黑人儿童的恶性黑色素瘤:诱发前驱病变及治疗
J Natl Med Assoc. 2004 Oct;96(10):1368-73.
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The association between naevi and melanoma in populations with different levels of sun exposure: a joint case-control study of melanoma in the UK and Australia.
不同日晒水平人群中痣与黑色素瘤的关联:英国和澳大利亚黑色素瘤联合病例对照研究
Br J Cancer. 1998;77(3):505-10. doi: 10.1038/bjc.1998.81.
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Melanoma risk factors and atypical moles.黑色素瘤风险因素与非典型痣
West J Med. 1994 Apr;160(4):343-50.
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Relation between phenotype and banal melanocytic naevi.表型与普通黑素细胞痣之间的关系。
Br Med J (Clin Res Ed). 1987 Jan 17;294(6565):152-4. doi: 10.1136/bmj.294.6565.152.
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Correlation of clinical pigmentary characteristics with histopathologically-confirmed dysplastic nevi in nonfamilial melanoma patients. Studies of melanocytic nevi IX.非家族性黑色素瘤患者临床色素沉着特征与组织病理学确诊的发育异常痣的相关性。黑素细胞痣的研究IX。
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