• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

脑苷脂在酒精性多发性神经病中的作用。

Effects of cerebral gangliosides in the alcoholic polyneuropathies.

作者信息

Mamoli B, Brunner G, Mader R, Schanda H

出版信息

Eur Neurol. 1980;19(5):320-6. doi: 10.1159/000115168.

DOI:10.1159/000115168
PMID:6249608
Abstract

In chronic alcoholic patients with a slight or moderate polyneuropathy the effect of gangliosides at a daily dosage of 20 mg was investigated. A clinical improvement represented by a reappearance of the Achilles reflex and/or marked reduction of hypoaesthesia was found in the treated group. No significant changes in motor function were observed. No significant variation of the electrophysiological examination was found.

摘要

在患有轻度或中度多发性神经病的慢性酒精中毒患者中,研究了每日剂量为20毫克的神经节苷脂的效果。在治疗组中发现,以跟腱反射重现和/或感觉减退明显减轻为代表的临床改善。未观察到运动功能有显著变化。电生理检查未发现显著差异。

相似文献

1
Effects of cerebral gangliosides in the alcoholic polyneuropathies.脑苷脂在酒精性多发性神经病中的作用。
Eur Neurol. 1980;19(5):320-6. doi: 10.1159/000115168.
2
Electromyographic study of diabetic and alcoholic polyneuropathic patients treated with gangliosides.用神经节苷脂治疗的糖尿病性和酒精性多神经病患者的肌电图研究
Muscle Nerve. 1982 May-Jun;5(5):351-6. doi: 10.1002/mus.880050503.
3
Ganglioside treatment of alcoholic neuropathies: experimental and clinical aspects.神经节苷脂治疗酒精性神经病:实验与临床方面
Pharmacol Biochem Behav. 1983;18 Suppl 1:51-4. doi: 10.1016/0091-3057(83)90146-6.
4
[Clinical and electromyographic study of the therapeutic effectiveness and general tolerability of a new mixture of internal ester gangliosides in patients with peripheral neuropathy caused by alcoholism].[关于一种新型内脂神经节苷脂混合物对酒精所致周围神经病患者治疗效果及总体耐受性的临床与肌电图研究]
Minerva Med. 1990 Nov;81(11):807-13.
5
[Immediate effects of cerebral gangliosides in peripheral neuropathies: electromyographic evaluation].[脑神经节苷脂在外周神经病变中的即时效应:肌电图评估]
Arq Neuropsiquiatr. 1984 Dec;42(4):356-61. doi: 10.1590/s0004-282x1984000400007.
6
[Use of cerebral cortex gangliosides in peripheral neuropathies].[大脑皮质神经节苷脂在外周神经病变中的应用]
Arq Neuropsiquiatr. 1981 Dec;39(4):444-9. doi: 10.1590/s0004-282x1981000400010.
7
A double blind placebo controlled trial of mixed gangliosides in diabetic peripheral and autonomic neuropathy.
Adv Exp Med Biol. 1984;174:607-24. doi: 10.1007/978-1-4684-1200-0_52.
8
Double-blind controlled trial of purified brain gangliosides in amyotrophic lateral sclerosis and experience with peripheral neuropathies.纯化脑苷脂治疗肌萎缩侧索硬化症的双盲对照试验及周围神经病治疗经验
Adv Exp Med Biol. 1984;174:565-73. doi: 10.1007/978-1-4684-1200-0_47.
9
Central and peripheral motor conduction time in chronic alcoholics with polyneuropathy and/or spasticity.患有多发性神经病和/或痉挛的慢性酒精中毒患者的中枢和外周运动传导时间
Funct Neurol. 1999 Jan-Mar;14(1):29-36.
10
[Alcoholic polyneuropathy. Electrophysiological and clinical findings in 85 patients (author's transl)].
Arch Psychiatr Nervenkr (1970). 1975 May 28;220(2):159-70. doi: 10.1007/BF00341648.

引用本文的文献

1
The Therapeutic Role of Gangliosides in Neurological Disorders.神经障碍治疗中的神经节苷脂作用
CNS Drugs. 1994 Mar;1(3):213-22. doi: 10.2165/00023210-199401030-00006.
2
Impairment, disability, or handicap in peripheral neuropathy: analysis of the use of outcome measures in clinical trials in patients with peripheral neuropathies.周围神经病变中的损伤、残疾或障碍:周围神经病变患者临床试验中结局指标使用情况的分析
J Neurol Neurosurg Psychiatry. 1995 Aug;59(2):165-9. doi: 10.1136/jnnp.59.2.165.
3
Gangliosides. Their role in clinical neurology.
Drugs. 1994 Apr;47(4):576-85. doi: 10.2165/00003495-199447040-00002.
4
Treatment of peripheral neuropathies.周围神经病变的治疗。
J Neurol Neurosurg Psychiatry. 1985 Dec;48(12):1193-207. doi: 10.1136/jnnp.48.12.1193.