Song C W
J Natl Cancer Inst. 1978 Mar;60(3):711-3. doi: 10.1093/jnci/60.3.711.
The effect of hyperthermia on vascular volume and vascular permeability of the Walker carcinoma 256, skin, and muscle of inbred SD male rats was investigated. Whereas heating at 43 degrees C for 1 hour induced a significant increase in the functional vascular volume and vascular permeability in the skin and muscle, it did not change these vascular functions in the tumors. The increased vascular volume in the normal tissues suggested an increased circulation, which may enhance the dissipation of heat and result in a differential effect of hyperthermia on normal tissues and tumors.
研究了热疗对近交系SD雄性大鼠Walker 256癌、皮肤和肌肉的血管容量及血管通透性的影响。在43℃加热1小时可使皮肤和肌肉的功能性血管容量及血管通透性显著增加，但肿瘤的这些血管功能未发生改变。正常组织中血管容量的增加提示循环增强，这可能会促进热量消散，从而导致热疗对正常组织和肿瘤产生不同的影响。
