Ziff E B
Nature. 1980 Oct 9;287(5782):491-9. doi: 10.1038/287491a0.
Messenger RNA synthesis by the DNA tumour viruses proceeds by a complex but versatile series of transcription and RNA processing steps. The major mechanistic features of this pathway are probably very similar to those used by the animal cell host itself. The viruses have, however, evolved intricate arrangements of protein coding sequences and sites for RNA initiation, polyadenylation and splicing which allow them to use their genetic information to maximum advantage.
DNA肿瘤病毒进行信使核糖核酸合成是通过一系列复杂但通用的转录和RNA加工步骤来实现的。该途径的主要机制特征可能与动物细胞宿主自身所使用的机制非常相似。然而，病毒已经进化出了蛋白质编码序列以及RNA起始、聚腺苷酸化和剪接位点的复杂排列，这使得它们能够最大限度地利用其遗传信息。
