DeSimone P A, East R, Powell R D
Hum Pathol. 1980 Sep;11(5 Suppl):535-9.
Biopsy specimens from 14 patients with oat cell carcinoma of the lung metastatic to bone marrow and from one patient with a localized tumor were examined for evidence of phagocytic activity by tumor cells. Phagocytic activity was observed in tumor cells in 90 per cent of the bone marrow biopsy specimens, 90 per cent of the cytology specimens, and 70 per cent of the biopsy specimens of other tissues. The cell most often phagocytosed was the leukocyte. Seventeen other tumors metastatic to bone marrow were studied and only one evidenced phagocytic activity.
对14例肺燕麦细胞癌骨髓转移患者的活检标本以及1例局限性肿瘤患者的活检标本进行检查，以寻找肿瘤细胞吞噬活性的证据。在90%的骨髓活检标本、90%的细胞学标本以及70%的其他组织活检标本中观察到肿瘤细胞具有吞噬活性。最常被吞噬的细胞是白细胞。对另外17例骨髓转移肿瘤进行了研究，只有1例有吞噬活性的证据。
