Walker J M, Akil H, Watson S J
Science. 1980 Dec 12;210(4475):1247-9. doi: 10.1126/science.6254152.
alpha-Melanocyte-stimulating hormone (alpha-MSH), a modified fragment of adrenocorticotropic hormone, derives from the same biosynthetic route as beta-endorphin and is stored by the same arcuate neurons. Microinjection of alpha-melanocyte-stimulating hormone and several related peptides into the periaqueductal gray matter significantly reduced responsiveness to pain and had a behavioral profile similar to that produced by beta-endorphin.
α-黑素细胞刺激素（α-MSH）是促肾上腺皮质激素的一种修饰片段，与β-内啡肽源自相同的生物合成途径，并由相同的弓状神经元储存。向导水管周围灰质微量注射α-黑素细胞刺激素及几种相关肽可显著降低对疼痛的反应性，其行为表现与β-内啡肽产生的相似。
