Tam M R, Green W R, Nowinski R C
Cancer Res. 1980 Oct;40(10):3850-3.
Monoclonal antibodies against the envelope proteins [gp70 and p15(E)] of murine leukemia virus react with the cell surface of virus-infected cells. The specificity and potency of these antibodies exceed those observed with conventional polyvalent antisera. In cytotoxic assays, certain of the monoclonal anti-gp70 antibodies demonstrate 1000-fold differences in their titer on leukemic and normal thymus cells.
针对鼠白血病病毒包膜蛋白[gp70和p15(E)]的单克隆抗体可与病毒感染细胞的细胞表面发生反应。这些抗体的特异性和效力超过了传统多价抗血清所观察到的情况。在细胞毒性试验中，某些抗gp70单克隆抗体在白血病细胞和正常胸腺细胞上的效价显示出1000倍的差异。
