人类β-珠蛋白基因的核苷酸序列。
The nucleotide sequence of the human beta-globin gene.
作者信息
Lawn R M, Efstratiadis A, O'Connell C, Maniatis T
出版信息
Cell. 1980 Oct;21(3):647-51. doi: 10.1016/0092-8674(80)90428-6.
PMID:6254664
Abstract
We report the complete nucleotide sequence of the human beta-globin gene. The purpose of this study is to obtain information necessary to study the evolutionary relationships between members of the human beta-like globin gene family and to provide the basis for comparing normal beta-globin genes with those obtained from the DNA of individuals with genetic defects in hemoglobin expression.
摘要
我们报道了人类β-珠蛋白基因的完整核苷酸序列。本研究的目的是获取研究人类β-珠蛋白样基因家族成员之间进化关系所需的信息，并为将正常β-珠蛋白基因与从血红蛋白表达存在遗传缺陷的个体的DNA中获得的基因进行比较提供基础。
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