Vaidyanathan S, Rao M S, Bapna B C, Chary K S, Palaniswamy R
J Urol. 1980 Dec;124(6):869-71. doi: 10.1016/s0022-5347(17)55706-7.
Beta-adrenergic activity in the proximal urethra was studied in 15 patients with neurogenic bladder dysfunction owing to spinal cord injury or to neurogenic disease. Maximum urethral closure pressure was recorded before and after the administration of terbutaline, a beta-2 agonist. The average decrease in maximum urethral closure pressure after subcutaneous injection of terbutaline was 40.46 per cent and this was significant (p less than 0.001). The clinical implications of this finding are discussed.
对15例因脊髓损伤或神经源性疾病导致神经源性膀胱功能障碍的患者,研究了其近端尿道的β-肾上腺素能活性。在给予β-2激动剂特布他林前后记录最大尿道闭合压。皮下注射特布他林后,最大尿道闭合压平均下降40.46%,这一结果具有显著性(p<0.001)。本文讨论了该发现的临床意义。