Thind P, Lose G, Colstrup H, Andersson K E
Department of Urology, Rigshospitalet, University of Copenhagen, Denmark.
Scand J Urol Nephrol. 1993;27(1):31-8. doi: 10.3109/00365599309180411.
The effects of terbutaline, propranolol, carbachol, and atropine on the static urethral closure function were investigated in 20 healthy women. Terbutaline caused a statistically reduction of the urethral pressure in the high pressure zone, but not at the bladder neck or in the distal urethra. The other drugs caused no significant pressure changes. None of the drugs used produced significant changes in the static viscoelastic properties, elastance, and hysteresis of the resting urethra. It is suggested that terbutaline partly reduces intraurethral pressure by reducing muscular tone in the rhabdosphincter and pelvic floor.
在20名健康女性中研究了特布他林、普萘洛尔、卡巴胆碱和阿托品对静态尿道闭合功能的影响。特布他林使高压区尿道压力有统计学意义的降低，但膀胱颈或尿道远端无此变化。其他药物未引起显著的压力变化。所使用的药物均未使静息尿道的静态粘弹性特性、弹性和滞后现象发生显著改变。提示特布他林通过降低横纹括约肌和盆底的肌肉张力部分降低尿道内压。
