Popper H
Zentralbl Allg Pathol. 1980;124(5):403-9.
Hepatoblastomas are more common in childhood but extremely rare in adults. A further case of hepatoblastoma in an adult is reported: The tumor consisted of two components, epithelial and mesenchymal ones. Both were well-separated from each other and showed different ways of metastasizing in to lymphatic vessels and lymph nodes or in to blood vessels and lung, respectively. It is concluded that hepatoblastomas of mixed type originate from two different cell types: The tubular and, sometimes, acinar malignant cells originate from the epithelium of the foregut and the osteo-osteoid-chondromatous malignant component is derived from mesenchymal cell of the coelomic wall.
肝母细胞瘤在儿童期更为常见,但在成人中极为罕见。本文报道了一例成人肝母细胞瘤:肿瘤由上皮和间充质两种成分组成。两者彼此分隔良好,分别显示出向淋巴管和淋巴结或向血管和肺转移的不同方式。结论是混合型肝母细胞瘤起源于两种不同的细胞类型:管状以及有时为腺泡状的恶性细胞起源于前肠上皮,而骨-骨样-软骨瘤样恶性成分则来源于体腔壁的间充质细胞。