Frisina N, De Pasquale R, Lasco A, Buemi M, Macrì I, Costa G
Boll Soc Ital Biol Sper. 1980 Jul 15;56(13):1380-4.
The Authors have studied corticosteron output and tissue levels of cAMP during superfusion with ACTH and/or PGE2 before and after preincubation with indometacin (2 microgram/ml) in beef adrenal glands isolated and superfused with Ringer solution. The Authors on the basis of Mieir studies, conclude that PGE2 can be considered as fixed intermediares of the corticosteroidogenetic action of ACTH.
作者们研究了在分离并用林格氏液灌注的牛肾上腺中，用吲哚美辛（2微克/毫升）预孵育前后，用促肾上腺皮质激素（ACTH）和/或前列腺素E2（PGE2）进行超灌注期间皮质醇的分泌量和环磷酸腺苷（cAMP）的组织水平。基于米尔的研究，作者们得出结论，PGE2可被视为ACTH皮质类固醇生成作用的固定中间介质。
