Panzram G, Ruttmann B
Schweiz Med Wochenschr. 1978 Feb 18;108(7):221-5.
The 10-year course of diabetes in 250 patients detected by glucosuria screening in 1963 was evaluated in an inter-individual pair comparison with patients from the same territory admitted during the same calendar year. Pairs were grouped according to age, sex, and weight. Judged by mortality, survival time, causes of death, and vascular complications, the medium-term prognosis was not improved by screening, although in the screening group a strict diet could be maintained to a greater extent. Problems of evaluation and effectiveness of mass examination in chronic diseases are discussed. Glucosuria and hyperglycemia do not suffice as screening criteria for the early recognition of the complex risk of arteriosclerosis in maturity onset diabetes. Multi-screening in groups with especially high diabetes risk is expected to yield higher effectiveness than the mass screening hitherto performed.
对1963年通过糖尿筛查检出的250例患者的10年糖尿病病程，与同年在同一地区住院的患者进行个体间配对比较评估。配对根据年龄、性别和体重分组。从死亡率、生存时间、死因和血管并发症判断，筛查并未改善中期预后，尽管筛查组能更大程度地维持严格饮食。讨论了慢性病群体检查的评估问题和有效性。糖尿和高血糖不足以作为早期识别成年型糖尿病中复杂动脉硬化风险的筛查标准。预计在糖尿病风险特别高的群体中进行多重筛查比迄今开展的群体筛查能产生更高的有效性。
