Poisson M, Bleibel J M, Regnier A, Mashaly R, Le Bigot P, Danis M, Buge A
Sem Hop. 1980;56(47-68):1979-82.
The authors report an observation of african trypanosomiasis due to Trypanosoma Gambiense, clinical signs included massive and progressive hemiplegia, papillary edema and vascular shift from median line at arteriography. These pseudo tumoral clinical features are unusual in this disease. Asymetrical heterogenous hypodensities of the centrum semioval are dominant in the initial CT scanner aspect. The confrontation of CT scanner images to the clinical and evolutive data suggests the presence of associated cerebral edema and demyelination. With treatment, hypodensities were regressing while images of subcortical atrophy appeared. Lastly, in spite of severe general signs and the importance of neurological deficit, arsenical treatment associated with high doses of corticotherapy lead to a rapid improvement.
作者报告了一例由冈比亚锥虫引起的非洲锥虫病观察病例，临床症状包括进行性大面积偏瘫、视乳头水肿以及动脉造影显示血管从中线移位。这些类似肿瘤的临床特征在该疾病中并不常见。最初的CT扫描显示半卵圆中心不对称性不均匀低密度影占主导。CT扫描图像与临床及病情发展数据对比提示存在相关的脑水肿和脱髓鞘。经过治疗，低密度影逐渐消退，同时出现皮质下萎缩影像。最后，尽管有严重的全身症状和神经功能缺损，但砷剂治疗联合大剂量皮质激素治疗使病情迅速改善。
