Shimizu N, Shimizu Y, Kondo I, Woods C, Wegner T
Cytogenet Cell Genet. 1981;29(1):26-31. doi: 10.1159/000131548.
Bovine embryonic trachea cells were hybridized with mouse A9 cells deficient in hypoxanthine phosphoribosyltransferase, and cattle-mouse hybrid cells clones were isolated after HAT/ouabain selection. In these interspecific cell hybrids, bovine glucose-6-phosphate dehydrogenase, alpha-galactosidase, and phosphoglycerate kinase were expressed concordantly with bovine HPRT. Their expression depended on the presence of bovine X chromosome. These data indicated that the genes for G6PD, PGK, and HPRT are linked and can be assigned to the bovine X chromosome.
将牛胚胎气管细胞与次黄嘌呤磷酸核糖基转移酶缺陷的小鼠A9细胞杂交，经HAT/乌本苷选择后分离出牛-鼠杂交细胞克隆。在这些种间细胞杂种中，牛葡萄糖-6-磷酸脱氢酶、α-半乳糖苷酶和磷酸甘油酸激酶与牛次黄嘌呤磷酸核糖基转移酶协同表达。它们的表达取决于牛X染色体的存在。这些数据表明，葡萄糖-6-磷酸脱氢酶、磷酸甘油酸激酶和次黄嘌呤磷酸核糖基转移酶的基因是连锁的，并且可以定位到牛X染色体上。
