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噬菌体T4基因组的限制酶切图谱。

A restriction map of the bacteriophage T4 genome.

作者信息

O'Farrell P H, Kutter E, Nakanishi M

出版信息

Mol Gen Genet. 1980;179(2):421-435. doi: 10.1007/BF00425473.

DOI:10.1007/BF00425473
PMID:6258018
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2868831/
Abstract

We report a detailed restriction map of the bacteriophage T4 genome and the alignment of this map with the genetic map. The sites cut by the enzymes Bg/II, XhoI, KpnI, SalI, PstI, EcoRI and HindIII have been localized. Several novel approaches including two-dimensional (double restriction) electrophoretic separations were used.

摘要

我们报告了噬菌体T4基因组的详细限制酶切图谱以及该图谱与遗传图谱的比对情况。已确定了被Bg/II、XhoI、KpnI、SalI、PstI、EcoRI和HindIII等酶切割的位点。使用了包括二维（双重限制酶切）电泳分离在内的几种新方法。

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1
A restriction map of the bacteriophage T4 genome.噬菌体T4基因组的限制酶切图谱。
Mol Gen Genet. 1980;179(2):421-435. doi: 10.1007/BF00425473.
2
[Restriction mapping of T4 bacteriophage late gene region which contains the origins of DNA replication].[包含DNA复制起始点的T4噬菌体晚期基因区域的限制酶切图谱]
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Gene. 1981 Dec;16(1-3):107-18. doi: 10.1016/0378-1119(81)90067-6.

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本文引用的文献

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Isolation and characterization of DNA fragments containing the dihydrofolate-reductase gene of coliphage T4.含有大肠杆菌噬菌体T4二氢叶酸还原酶基因的DNA片段的分离与特性分析。
Gene. 1980 May;9(3-4):271-85. doi: 10.1016/0378-1119(90)90327-n.
2
The generation and analysis of clones containing bacteriophage T4 DNA fragments.包含噬菌体T4 DNA片段的克隆的产生与分析。
J Mol Biol. 1980 Feb 25;137(2):235-48. doi: 10.1016/0022-2836(80)90327-7.
3
Mapping of deletions in a non-essential region of the phage T4 genome.噬菌体T4基因组非必需区域缺失的定位
从宿主到噬菌体代谢：噬菌体 T4 接管. 的热门故事
Viruses. 2018 Jul 21;10(7):387. doi: 10.3390/v10070387.
4
Isolation of the TRP2 and the TRP3 genes of Saccharomyces cerevisiae by functional complementation in yeast.通过酵母中的功能互补作用分离酿酒酵母的 TRP2 和 TRP3 基因。
Curr Genet. 1982 May;5(1):39-46. doi: 10.1007/BF00445739.
5
Plasmid-like DNAs in the commercially important mushroom genus Agaricus.商业上重要的蘑菇属金针菇中的质粒样 DNA。
Curr Genet. 1984 Oct;8(8):615-9. doi: 10.1007/BF00395707.
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Possible chromosomal location for the killer determinant in Torulopsis glabrata.光滑球拟酵母杀伤决定因子的可能染色体定位。
Curr Genet. 1984 Feb;8(2):115-9. doi: 10.1007/BF00420229.
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Characterization of inverted repeat sequences and ribosomal RNA genes of chloroplast DNA from Chlorella ellipsoidea.小球藻叶绿体 DNA 中反向重复序列和核糖体 RNA 基因的特征。
Curr Genet. 1983 Nov;7(6):481-7. doi: 10.1007/BF00377614.
8
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Curr Genet. 1983 Jun;7(3):201-10. doi: 10.1007/BF00434891.
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J Mol Biol. 1968 Dec;38(3):395-411. doi: 10.1016/0022-2836(68)90394-x.
10
Characterization of a new class of deletions of the D region of the bacteriophage T4 genome.噬菌体T4基因组D区域一类新缺失的特征分析
Virology. 1975 Mar;64(1):144-5. doi: 10.1016/0042-6822(75)90086-0.