Piéron R, Mafart Y, Lesobre B, Meyniel D, Varsat B
Sem Hop. 1981;57(1-2):16-21.
One hundred and twenty-three cases of sickle-cell trait (122 negro immigrants) are studied in a department of internal medicine. The frequencies of G6PD deficiency, anemia, splenomegaly and tuberculosis are neighbouring at the negro without hemoglobinopathy. The relationship between the sickle-cell trait and the reason of admission of the final diagnosis il likely in 2,4 % of the cases, doubtfully in 15,4 %, null in the other cases. The occasional (hemolytic, thrombotic, painful, visceral, osseous) manifestations of the sickle-cell trait (apart from the constant hyposthenuria) and their mechanism are summarized and discussed.
在内科对123例镰状细胞性状患者（122例为黑人移民）进行了研究。葡萄糖-6-磷酸脱氢酶（G6PD）缺乏症、贫血、脾肿大和结核病的发生率与无血红蛋白病的黑人相近。镰状细胞性状与最终诊断的入院原因之间的关系在2.4%的病例中可能存在，在15.4%的病例中存在疑问，在其他病例中不存在。总结并讨论了镰状细胞性状的偶发（溶血、血栓形成、疼痛、内脏、骨骼）表现（除持续的低渗尿外）及其机制。
