氨基葡萄糖对水疱性口炎病毒与禽肉瘤病毒表型混合的影响。
Effect of glucosamine on phenotype mixing of vesicular stomatitis virus with avian sarcoma virus.
作者信息
Ogura H, Fujiwara T
出版信息
Acta Med Okayama. 1980 Dec;34(6):355-9. doi: 10.18926/AMO/30531.
The effect of glucosamine on phenotypic mixing between vesicular stomatitis virus (VSV) and avian sarcoma virus (ASV) was studied. Phenotypic mixing decreased with increase in glucosamine concentration, and, in the presence of 20 mM glucosamine, was no longer detectable. In the presence of 20 mM glucosamine, cells still produced 10(2)--10(3) focus forming units (FFU) of ASV and 10(6) plaque forming units (PFU) of VSV per milliliter. These results suggest that cells producing a relatively large amount of ASV (more than 10(3) FFU/ml) are essential for phenotypic mixing of VSV with ASV.
研究了氨基葡萄糖对水疱性口炎病毒（VSV）和禽肉瘤病毒（ASV）之间表型混合的影响。表型混合随氨基葡萄糖浓度的增加而降低，在20 mM氨基葡萄糖存在的情况下，不再能检测到。在20 mM氨基葡萄糖存在的情况下，细胞每毫升仍产生10²-10³个禽肉瘤病毒集落形成单位（FFU）和10⁶个水疱性口炎病毒蚀斑形成单位（PFU）。这些结果表明，产生相对大量禽肉瘤病毒（超过10³ FFU/ml）的细胞对于水疱性口炎病毒与禽肉瘤病毒的表型混合至关重要。
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