具核梭杆菌培养液诱导人淋巴母细胞样P3HR-1细胞中EB病毒抗原
Induction of Epstein-Barr virus antigens in human lymphoblastoid P3HR-1 cells with culture fluid of Fusobacterium nucleatum.
作者信息
Ito Y, Kishishita M, Yanase S
出版信息
Cancer Res. 1980 Nov;40(11):4329-30.
PMID:6258779
Abstract
Epstein-Barr virus-associated early antigen and viral capsid antigen were efficiently induced in human lymphoblastoid P3HR-1 cells with culture fluid of Fusobacterium nucleatum, a member of the indigenous microbial flora of the human host. This finding may suggest a new approach to assess the possible role of the "cofactor(s)" in the etiology of Epstein-Barr virus-related diseases.
摘要
人类宿主固有微生物群成员具核梭杆菌的培养液可在人淋巴母细胞样P3HR-1细胞中有效诱导爱泼斯坦-巴尔病毒相关早期抗原和病毒衣壳抗原。这一发现可能提示一种新方法，用以评估“辅助因子”在爱泼斯坦-巴尔病毒相关疾病病因学中的可能作用。
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