Graham A R, Payne C M, Nagle R B
Am J Pathol. 1981 Mar;102(3):359-66.
Type IV nuclear bodies were found in all renal biopsies obtained from 14 patients with crescentic glomerulonephritis (CGN) and in 8 of 43 control patients studied by light and electron microscopy. The mean ratio of Type IV nuclear bodies per 10 tubular cross-sections examined was 0.67 +/- 0.27 for the CGN cases, which was significantly different from 0.09 +/- 0.26 obtained for the controls (P less than 0.05). Type IV nuclear bodies were most commonly seen in the epithelial cells of proximal tubules but were also seen occasionally in interstitial fibroblasts and cells of a collecting duct and a developing crescent.
在对14例新月体性肾小球肾炎（CGN）患者进行的所有肾活检组织以及43例对照患者中的8例进行光镜和电镜检查时，均发现了IV型核小体。CGN病例每10个检查的肾小管横切面中IV型核小体的平均比例为0.67±0.27，与对照组的0.09±0.26有显著差异（P<0.05）。IV型核小体最常见于近端小管的上皮细胞中，但偶尔也可见于间质成纤维细胞、集合管细胞和正在形成的新月体中。
