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男同性恋者中巨细胞病毒感染的患病率。

Prevalence of cytomegalovirus infection in homosexual men.

作者信息

Drew W L, Mintz L, Miner R C, Sands M, Ketterer B

出版信息

J Infect Dis. 1981 Feb;143(2):188-92. doi: 10.1093/infdis/143.2.188.

DOI:10.1093/infdis/143.2.188
PMID:6260871
Abstract

Cytomegalovirus (CMV) was cultured from the urine of 14 of 190 homosexual but none of 101 heterosexual men attending a venereal disease clinic (P less than 0.005). Viruria was confined to men less than 30 years of age and was present in 14% of this group. Antibody to CMV was measured in the sera of 139 homosexual and 70 heterosexual men attending the same clinic and in 103 male volunteer blood donors. Titers were found in 94% of homosexual patients but in only 54% of heterosexual patients (P less than 0.005) and 43% of male volunteer blood donors (P less than 0.005). The data suggest that sexual transmission is an important mode of spread of CMV among adults and the homosexual men are at greater risk for CMV infections than are heterosexual men. Homosexual men might considered candidates for the evaluation of the efficacy of CMV vaccines in preventing horizontal transmission of infection.

摘要

从一家性病诊所的190名同性恋男性中的14人的尿液中培养出了巨细胞病毒(CMV),但在101名异性恋男性中均未培养出(P<0.005)。病毒尿仅限于30岁以下的男性,该组中有14%的人存在病毒尿。在同一家诊所就诊的139名同性恋男性、70名异性恋男性以及103名男性志愿献血者的血清中检测了CMV抗体。在94%的同性恋患者中发现了抗体滴度,但在异性恋患者中仅为54%(P<0.005),在男性志愿献血者中为43%(P<0.005)。数据表明,性传播是CMV在成年人中传播的一种重要方式,同性恋男性比异性恋男性感染CMV的风险更高。同性恋男性可能被视为评估CMV疫苗预防感染水平传播疗效的候选对象。

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Prevalence of cytomegalovirus infection in homosexual men.男同性恋者中巨细胞病毒感染的患病率。
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