同性恋男性中的巨细胞病毒感染。
Infection with cytomegalovirus in homosexual men.
作者信息
Coutinho R A, Wertheim-van Dillen P, Albrecht-van Lent P, Nagelkerke N, Kuipers H, van Bentum-van Haagen A, Rijsdijk T, van der Noordaa J
出版信息
Br J Vener Dis. 1984 Aug;60(4):249-52. doi: 10.1136/sti.60.4.249.
The prevalence and incidence of cytomegalovirus (CMV) infections were studied in a group of homosexual men. Of the 710 participants, 501 (70.6%) had complement fixing antibodies to CMV on entry to the study. During the follow up (maximum 23 months) 69 CMV infections were found: 50 primary infections among the 209 seronegative men (attack rate 27.3%), and 19 recurrent infections among the 501 seropositive men (attack rate 6.2%). The prevalence of antibody to CMV was correlated with four characteristics of the participants' lifestyles: duration of homosexual activity, number of different sexual partners, history of syphilis, and anal sexual contact. Among the seronegative men, the incidence of primary infection with CMV correlated with a history of syphilis and anal sexual contact. We conclude that infections with CMV are highly prevalent among homosexual men, and that anal sexual contact plays an important part in the transmission of this virus.
对一组男同性恋者的巨细胞病毒（CMV）感染的患病率和发病率进行了研究。在710名参与者中，501人（70.6%）在进入研究时具有针对CMV的补体结合抗体。在随访期间（最长23个月），发现69例CMV感染：209名血清阴性男性中有50例初次感染（感染率27.3%），501名血清阳性男性中有19例复发感染（感染率6.2%）。CMV抗体的患病率与参与者生活方式的四个特征相关：同性恋活动持续时间、不同性伴侣数量、梅毒病史和肛交。在血清阴性男性中，CMV初次感染的发生率与梅毒病史和肛交相关。我们得出结论，CMV感染在男同性恋者中非常普遍，并且肛交在这种病毒的传播中起重要作用。
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