Henning J M, Zentall T R
Am J Psychol. 1981 Mar;94(1):125-34.
The effects of ACTH 4-10 on rats' imitation learning was examined during the acquisition and extinction of a bar-press response for water reinforcement. Rats were exposed to either a bar-pressing conspecific (OB), an experimentally naive conspecific (ON), or an empty box (OE) during bar-press acquisition. In a factorial design, each rat was then exposed to one of the same three conditions during extinction. An 80 mcg dose of ACTH 4-10 was administered to half of the rats in each group prior to observation. Performance differences during acquisition were generally small, but significant performance differences during extinction were found. Social facilitation was indicated by the finding that rats extinguished in the presence of a conspecific exhibited significantly greater resistance to extinction than rats extinguished in the presence of an empty box. An imitation effect was also found. Rats that observed a bar-pressing conspecific during both acquisition and extinction (group OB-OB) showed significantly greater resistance top extinction than did groups OB-ON, CB-OE, or OE-OE. There were no significant effects of the hormone, however, relative to saline controls.
在以水强化的压杆反应的习得和消退过程中，研究了促肾上腺皮质激素4 - 10（ACTH 4 - 10）对大鼠模仿学习的影响。在压杆习得期间，将大鼠暴露于按压杠杆的同种动物（OB）、实验新手同种动物（ON）或空箱（OE）环境中。在析因设计中，然后在消退期间，将每只大鼠再次暴露于相同的三种条件之一。在观察前，给每组一半的大鼠注射80微克剂量的ACTH 4 - 10。习得期间的表现差异通常较小，但在消退期间发现了显著的表现差异。发现与在空箱环境中消退的大鼠相比，在同种动物存在下消退的大鼠对消退表现出显著更强的抵抗力，这表明了社会促进作用。还发现了一种模仿效应。在习得和消退期间都观察到按压杠杆同种动物的大鼠（OB - OB组）比OB - ON组、CB - OE组或OE - OE组表现出对消退更强的抵抗力。然而，相对于生理盐水对照组，该激素没有显著影响。
