Tuimala R J, Kauppila A J, Viinikka L, Ylikorkala O
Horm Metab Res. 1981 Mar;13(3):174-6. doi: 10.1055/s-2007-1019208.
In order to assess the effects of Na 872 infusion on maternal endocrinology during late pregnancy, we measured serum estradiol, estriol, progesterone, human placental lactogen, follicle simulating hormone, prolactin, cyclic adenosine monophosphate, cortisol and insulin before, during and after Na 872 infusion (bromhexine 2 mg/min for one hour) in ten mothers. As compared to six control mothers, no changes could be observed. This suggests that the claimed maturing effect of Na 872 on the fetal lungs is not mediated by the hormonal changes measurable in maternal blood.
为了评估在妊娠晚期输注氨溴索对母体内分泌的影响,我们在10名母亲输注氨溴索(溴己新2毫克/分钟,持续1小时)之前、期间和之后测量了血清雌二醇、雌三醇、孕酮、人胎盘催乳素、促卵泡激素、催乳素、环磷酸腺苷、皮质醇和胰岛素。与6名对照母亲相比,未观察到变化。这表明,所宣称的氨溴索对胎儿肺部的成熟作用并非由母体血液中可测量的激素变化介导。