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澳大利亚传染性支气管炎病毒：通过中和试验鉴定出9个亚型

Australian infectious bronchitis viruses: identification of nine subtypes by a neutralisation test.

作者信息

Wadey C N, Faragher J T

出版信息

Res Vet Sci. 1981 Jan;30(1):70-4. doi: 10.1016/S0034-5288(18)32611-0.

DOI:10.1016/S0034-5288(18)32611-0
PMID:6264556
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7125644/
Abstract

The antigenic relationships between 17 Australian infectious bronchitis viruses, including six vaccine viruses, were studied by a neutralisation test using a plaque reduction method in chick embryo kidney cell monolayers. The 17 viruses formed nine distinct subtypes. Antiserum to each subtype had a high titre to viruses of the same subtype and a lower titre to viruses of different subtypes. The heterologous titres of sera varied widely.

摘要

采用蚀斑减少法，在鸡胚肾细胞单层上进行中和试验，研究了17株澳大利亚传染性支气管炎病毒（包括6株疫苗病毒）之间的抗原关系。这17株病毒形成了9个不同的亚型。针对每个亚型的抗血清对同一亚型的病毒具有高滴度，而对不同亚型的病毒具有较低滴度。血清的异源滴度差异很大。

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本文引用的文献

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Persistent antigenic variation of influenza A viruses after incomplete neutralization in ovo with heterologous immune serum.甲型流感病毒在卵内用异源免疫血清进行不完全中和后出现持续的抗原变异。
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LACK OF CORRELATION BETWEEN INFECTIVITY, SEROLOGIC RESPONSE AND CHALLENGE RESULTS IN IMMUNIZATION WITH AN AVIAN INFECTIOUS BRONCHITIS VACCINE.禽传染性支气管炎疫苗免疫中感染性、血清学反应与攻毒结果之间缺乏相关性。
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Relationship between immunity and serum-neutralization titers in chickens inoculated with three infectious bronchitis vaccines.接种三种传染性支气管炎疫苗的鸡的免疫力与血清中和效价之间的关系
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Some characteristics of isolates of infectious bronchitis virus from commercial vaccines.来自商业疫苗的传染性支气管炎病毒分离株的一些特征。
Avian Dis. 1972 Jul-Sep;16(4):746-55.
8
Serological comparisons of strains of infectious bronchitis virus using plaque-purified isolants.使用蚀斑纯化分离株对传染性支气管炎病毒株进行血清学比较。
Avian Dis. 1974 Apr-Jun;18(2):231-9.
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Avian infectious bronchitis virus characteristics of an inhibitor found in serum.血清中发现的一种抑制剂对禽传染性支气管炎病毒的作用特性
Arch Gesamte Virusforsch. 1973;40(1):93-104. doi: 10.1007/BF01242641.
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The neutralizing characteristics of strains of infectious bronchitis virus as measured by the constant-virus variable-serum method in chicken tracheal cultures.通过鸡气管培养物中的恒定病毒可变血清法测定传染性支气管炎病毒毒株的中和特性。
Avian Dis. 1975 Jan-Mar;19(1):82-90.