近期一株澳大利亚传染性支气管炎病毒分离株的一些免疫学方面
Some immunological aspects of a recent Australian isolate of infectious bronchitis virus.
作者信息
Chubb R C, Wells B A, Cumming R B
出版信息
Aust Vet J. 1976 Aug;52(8):378-81. doi: 10.1111/j.1751-0813.1976.tb09494.x.
Abstract
An infectious bronchitis virus, designated G48, isolated from birds during an outbreak of nephritis in a previously vaccinated broiler flock, overcame the resistance induced in birds vaccinated with 2 commercially available vaccines. Birds vaccinated with the A isolate of infectious bronchitis resisted challenge with this new virus. Cross neutralisation studies revealed that the new virus was serologically distinct from the 4 viruses tested. Homologous antiserum to G48 did not neutralise the other viruses and only antiserum to the A virus completely neutralised the new virus.
摘要
一种从先前接种过疫苗的肉鸡群肾炎暴发期间的鸟类中分离出的传染性支气管炎病毒，命名为G48，克服了用两种市售疫苗接种的鸟类所诱导的抵抗力。用传染性支气管炎A株疫苗接种的鸟类对这种新病毒具有抵抗力。交叉中和试验表明，这种新病毒在血清学上与所检测的4种病毒不同。G48的同源抗血清不能中和其他病毒，只有A病毒的抗血清能完全中和这种新病毒。
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