一种芳香维甲酸（Ro 10-9359）对病毒致瘤作用的抑制效果。
Inhibitory effects of an aromatic retinoid (Ro 10-9359) on viral tumorigenesis.
作者信息
Frankel J W, Horton E J, Winters A L, Samis H V, Ito Y
出版信息
Intervirology. 1980;14(5-6):321-5. doi: 10.1159/000149203.
PMID:6265402
Abstract
Prophylactic treatment of hamsters and chickens with an aromatic retinoid (Ro 10-9359) inhibited Rous sarcoma virus (RSV) tumorigenesis. Retinoid administration to chickens with RSV-induced tumors resulted in tumor regression and/or confinement to the primary site. The retinoid also exerted a therapeutic effect on Shope virus papilloma development in the skin of rabbits.
摘要
用一种芳香维甲酸（Ro 10-9359）对仓鼠和鸡进行预防性治疗可抑制劳氏肉瘤病毒（RSV）的致瘤作用。给患有RSV诱导肿瘤的鸡施用维甲酸会导致肿瘤消退和/或局限于原发部位。这种维甲酸对兔皮肤中的肖普病毒乳头瘤发展也具有治疗作用。
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