Tuganowski W, Kopeć P, Kaszuba M, Glanc A
Pol J Pharmacol Pharm. 1981 Jan-Feb;33(1):49-52.
Propranolol introduced by a cut-end method into atrial trabeculae evoked negative inotropic response without any significant changes in basic electrical parameters. This effect was resistant to noradrenaline but not to dibutyryl cAMP. These results suggest that existence of intracellular beta adrenoreceptors involved in the control of the contraction.
通过断端法将普萘洛尔引入心房小梁可诱发负性肌力反应,而基本电参数无任何显著变化。这种效应对去甲肾上腺素具有抗性,但对二丁酰环磷腺苷不具有抗性。这些结果表明,存在参与收缩控制的细胞内β肾上腺素能受体。