Tamari H, Matsukura M, Matsuda I, Ueda K, Ohtsuka H
Brain Dev. 1981;3(1):87-91. doi: 10.1016/s0387-7604(81)80010-1.
An acute variant of subacute sclerosing panencephalitis (SSPE) was described in a 5-year-old boy who showed rapid progression of coma within 14 days of right hemiplegia. He had measles at 3 years of age. The diagnosis of SSPE was based on the following findings: high anti-measles antibody titer in the serum and in the spinal fluid, periodic complex of EEG, and typical pathological changes of the brain. Treatment with transfer factor failed to improve the worsening clinical course. It is suggested that SSPE should be considered in the differential diagnosis of acute fulminating encephalitides or intracranial vascular lesions.
一名5岁男孩被诊断为亚急性硬化性全脑炎（SSPE）的急性变异型，该男孩在右侧偏瘫后14天内迅速陷入昏迷。他3岁时患过麻疹。SSPE的诊断基于以下发现：血清和脑脊液中抗麻疹抗体滴度高、脑电图周期性复合波以及典型的脑部病理变化。使用转移因子治疗未能改善病情恶化的临床过程。建议在急性暴发性脑炎或颅内血管病变的鉴别诊断中考虑SSPE。
