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暴发性亚急性硬化性全脑炎(SSPE)的诊断困境

Diagnostic dilemmas in fulminant subacute sclerosing panencephalitis (SSPE).

作者信息

Sarkar Nupur, Gulati Sheffali, Dar Lalit, Broor Shobha, Kalra Veena

机构信息

Departments of Pediatrics, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Indian J Pediatr. 2004 Apr;71(4):365-7. doi: 10.1007/BF02724111.

Abstract

This report describes an eleven-year-old boy with atypical features of subacute sclerosing panencephalitis (SSPE), a rare complication of measles. He had only visual symptoms for 2 months followed by rapid neurological worsening to a vegetative state in 10 days. A diagnosis of SSPE was made based on the history of measles, characteristic ocular findings, compatible magnetic resonance imaging and electroencephalographic changes, and elevated ratio of cerebrospinal fluid to serum anti-measles antibody titers.

摘要

本报告描述了一名11岁男孩,其患有亚急性硬化性全脑炎(SSPE)的非典型特征,这是麻疹的一种罕见并发症。他仅出现视觉症状2个月,随后在10天内迅速出现神经功能恶化至植物人状态。根据麻疹病史、特征性眼部表现、相符的磁共振成像和脑电图变化以及脑脊液与血清抗麻疹抗体滴度升高,做出了SSPE的诊断。

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