Schlosnagle D C, Someren A
Oral Surg Oral Med Oral Pathol. 1981 Aug;52(2):154-61. doi: 10.1016/0030-4220(81)90313-3.
An adenomatoid odontogenic tumor (AOT) which occurred in the maxilla of an 8-year-old boy was studied by the light and electron microscopy. The tumor was found to contain cells resembling preameloblasts, the stratum intermedium, and the stellate reticulum, suggesting its origin from the enamel organ, in agreement with previous reports. Characteristic ductlike structures are thought to be formed as a result of secretory activity of the tumor cells, rather than degeneration. Duct-lining cells ultrastructurally similar to preameloblasts were found to contain electron-dense granules. These granules are believed to play a role in secretion by tumor cells, a concept not previously considered. The results of previous ultrastructural studies of the AOT are reviewed and summarized.
对一名8岁男孩上颌骨发生的腺样牙源性肿瘤（AOT）进行了光镜和电镜研究。发现该肿瘤含有类似于成釉器前体细胞、中间层细胞和星网状层细胞，提示其起源于成釉器，这与既往报道一致。特征性的导管样结构被认为是肿瘤细胞分泌活动的结果，而非退变所致。电镜下发现导管内衬细胞与成釉器前体细胞相似，含有电子致密颗粒。这些颗粒被认为在肿瘤细胞分泌中起作用，这是一个此前未被考虑的概念。对既往腺样牙源性肿瘤超微结构研究结果进行了综述和总结。
