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Benzo(a)pyrene metabolism and blast transformation in peripheral blood mononuclear cells from smoking and nonsmoking populations and lung cancer patients.

作者信息

Jett J R, Moses H L, Branum E L, Taylor W F, Fontana R S

出版信息

Cancer. 1978 Jan;41(1):192-200. doi: 10.1002/1097-0142(197801)41:1<192::aid-cncr2820410128>3.0.co;2-0.

DOI:10.1002/1097-0142(197801)41:1<192::aid-cncr2820410128>3.0.co;2-0
PMID:626929
Abstract
摘要

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1
Benzo(a)pyrene metabolism and blast transformation in peripheral blood mononuclear cells from smoking and nonsmoking populations and lung cancer patients.吸烟人群、非吸烟人群及肺癌患者外周血单个核细胞中苯并(a)芘代谢与细胞转化
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Macromolecular binding of 3H-benzo(a)pyrene metabolites and lymphocyte transformation in patients with lung cancer, and in smoking and nonsmoking control subjects.肺癌患者以及吸烟和不吸烟对照受试者中³H-苯并(a)芘代谢产物的大分子结合与淋巴细胞转化
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A human plasma component that binds benzo(a)pyrene.一种能结合苯并(a)芘的人血浆成分。
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Interindividual variation in binding of benzo[a]pyrene to DNA in cultured human bronchi.培养的人支气管中苯并[a]芘与DNA结合的个体间差异。
Science. 1976 Dec 3;194(4269):1067-9. doi: 10.1126/science.982061.
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Carcinogenic benzo(a)pyrene metabolites bound to DNA: metabolic formation by human cultured lymphocytes and by human liver microsomes.与DNA结合的致癌性苯并(a)芘代谢物：人培养淋巴细胞和人肝微粒体的代谢形成
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Large interindividual variations in metabolism of benzo(alpha)pyrene by peripheral lung tissue from lung cancer patients.肺癌患者外周肺组织对苯并（α）芘的代谢存在较大个体差异。
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Measurement of benzo(a)pyrene metabolism in human monocytes.人体单核细胞中苯并(a)芘代谢的测定。
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Aryl hydrocarbon hydroxylase and benzo[a] pyrene metabolism in rodent liver and human cels.啮齿动物肝脏和人类细胞中的芳烃羟化酶与苯并[a]芘代谢
Ann N Y Acad Sci. 1980;349:232-46. doi: 10.1111/j.1749-6632.1980.tb29530.x.

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Jpn J Cancer Res. 1996 Jan;87(1):18-24. doi: 10.1111/j.1349-7006.1996.tb00194.x.
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Enhanced benzo(a)pyrene metabolism and formation of DNA adducts in monocytes of patients with lung cancer.肺癌患者单核细胞中苯并(a)芘代谢增强及DNA加合物的形成
J Cancer Res Clin Oncol. 1980;96(3):295-302. doi: 10.1007/BF00408102.
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Genetic differences in susceptibility to chemically induced myelotoxicity and leukemia.
化学诱导的骨髓毒性和白血病易感性的遗传差异。
Environ Health Perspect. 1981 Jun;39:11-22. doi: 10.1289/ehp.813911.
4
A genetic component of the variance of N-acetoxy-2-acetylaminofluorene-induced DNA damage in mononuclear leukocytes determined by a twin study.一项双胞胎研究确定的N-乙酰氧基-2-乙酰氨基芴诱导的单核白细胞DNA损伤变异中的遗传成分。
Hum Genet. 1983;65(2):181-4. doi: 10.1007/BF00286659.
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Bioavailability and biotransformation of the mutagenic component of particulate emissions present in motor exhaust samples.汽车尾气样本中存在的颗粒物排放诱变成分的生物利用度和生物转化
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Br J Cancer. 1990 Feb;61(2):195-206. doi: 10.1038/bjc.1990.37.