Bingham P M, Judd B H
Cell. 1981 Sep;25(3):705-11. doi: 10.1016/0092-8674(81)90177-x.
Results are described demonstrating that several X chromosomes of Drosophila melanogaster carrying the Wa (white-apricot) mutant allele also carry homology to the copia transposable element in distal 3C of the polytene chromosome map as assessed by situ hybridization. The locus of the Wa mutation, white, resides in distal 3C. We further show, using fine scale genetic mapping techniques, that the copia homology in distal 3C in Wa-bearing chromosomes is very tightly linked to the Wa mutation. Both the Wa mutation and the copia homology associated with it map to the central portion of the white locus.
结果表明,通过原位杂交评估,果蝇黑腹果蝇中携带Wa(白杏色)突变等位基因的几条X染色体在多线染色体图谱的3C远端也与copia转座元件具有同源性。Wa突变的位点white位于3C远端。我们进一步使用精细遗传图谱技术表明,携带Wa的染色体中3C远端的copia同源性与Wa突变紧密连锁。Wa突变及其相关的copia同源性都定位于white位点的中央部分。