Knudson M B, Amend J F, Stone E C
Cardiology. 1978;63(2):65-72. doi: 10.1159/000169883.
Electrocardiogram, atrial electrogram, phonocardiogram, aortic pressure, and left ventricular pressure were recorded during periods of induced atrial fibrillation in dogs anesthetized with a combination of morphine sulfate and pentobarbital sodium. Data were accumulated by selecting 50 cardiac cycles which terminated in ectopic ventricular electrical complexes, and comparing systolic time intervals (STI) following these beats with STI Following 50 normal ventricular complexes. Ectopic ventricular activation prolonged left ventricular pre-ejection period and external isovolumic contraction time, and reduced duration of left ventricular ejection time. These events resemble changes in STI observed following induction of atrial fibrillation from a sinus rhythm, but they are of significantly greater magnitude than the effects of atrial fibrillation alone.
在用硫酸吗啡和戊巴比妥钠联合麻醉的犬诱发心房颤动期间，记录心电图、心房电图、心音图、主动脉压力和左心室压力。通过选择50个以异位心室电复合波结束的心动周期，并将这些搏动后的收缩期时间间期（STI）与50个正常心室复合波后的STI进行比较来积累数据。异位心室激活延长了左心室射血前期和体外等容收缩时间，并缩短了左心室射血时间的持续时间。这些事件类似于从窦性心律诱发心房颤动后观察到的STI变化，但它们的幅度明显大于单独心房颤动的影响。
