Kostriken R, Morita C, Heffron F
Proc Natl Acad Sci U S A. 1981 Jul;78(7):4041-5. doi: 10.1073/pnas.78.7.4041.
The bacterial transposon Tn3 encodes a site-specific recombination system. The recombination requires the product of tnpR, a gene previously identified as a repressor of the transposase. This recombination is site specific and takes place somewhere within the sequence C-G-A-A-A-T-A-T-T-A-T-A-A-A-T-T-A-T-C but requires at least one additional sequence outside this. The phenotype of mutations in this recombination system suggests that transposition proceeds by a mechanism in which cointegrates are intermediates.
细菌转座子Tn3编码一种位点特异性重组系统。这种重组需要tnpR基因的产物，该基因先前被鉴定为转座酶的阻遏物。这种重组是位点特异性的，发生在序列C-G-A-A-A-T-A-T-T-A-T-A-A-A-T-T-A-T-C内的某个位置，但至少还需要该序列之外的一个额外序列。这个重组系统中突变的表型表明，转座是通过一种以共整合体为中间体的机制进行的。
