Ghéron G
Sem Hop. 1981;57(37-38):1515-20.
Synthetic progestogens are divided into three major groups of steroids which derive from the basic steroid nucleus. Several routes of administration can be used. The characteristics (progestomimetic, progestational, and hormonal) of the different progestogens are variable. The different compounds are therefore of therapeutic value in specific indications. For some of these a study of the literature was carried out. We studied : anomalies of the menstrual cycle (involving chronology, menstruation...); the premenstrual syndrome with or without benign mastopathy ; menopause (premenopause and established menopause). The differences in the tolerance of the different compounds in use are recalled, in connexion with contra-indications and major and minor side-effects. The wide differences between the various compounds can make the choice of the less than right progestogen greater than difficult.
合成孕激素分为三类主要的类固醇,它们源自基本的类固醇核。可以采用几种给药途径。不同孕激素的特性(类孕激素、孕激素和激素特性)各不相同。因此,不同的化合物在特定适应症中具有治疗价值。对于其中一些,我们进行了文献研究。我们研究了:月经周期异常(涉及时间顺序、月经……);伴有或不伴有良性乳腺病的经前综合征;更年期(绝经前期和已绝经)。文中回顾了不同使用中的化合物在耐受性方面的差异,以及禁忌症和主要及次要副作用。各种化合物之间的巨大差异使得选择不合适的孕激素变得极其困难。