Bozhinova S
Akush Ginekol (Sofiia). 1996;35(3):50-1.
The author's aim is to study the therapeutical possibilities and the side effects of Norkolut preparation, produced by the Pharmaceutical Plant Gedeon Richter-Budapest. Norkolut is a peroral gestagen containing 5 mg noretisteron in 1 tablet. The study included 40 women, age 17 to 52 who had been administered the preparation from 1 to 6 menstrual cycles--total 162. The main indications for its application were: climacteric bleeding with proved cystic hyperplasia, irregular menstrual cycles, myoma uteri cum metrorrhagia, perimenopause hormone replacement therapy, adenomyosis. The recorded effect of the preparation was very good with little side effects (7.5%). The author's conclusion is that Norkolut is quite suitable to be used in the everyday gynaecological practice in the treatment of the dysfunctional uterus bleeding, irregular menstrual cycles, in the hormone replacement therapy during menopause and for decreasing the complaints in adenomyosis.
作者的目的是研究由布达佩斯吉东·里奇特制药厂生产的诺古鲁特制剂的治疗可能性及其副作用。诺古鲁特是一种口服孕激素，每片含5毫克炔诺孕酮。该研究纳入了40名年龄在17至52岁之间的女性，她们服用该制剂1至6个月经周期，共计162个周期。其主要应用指征为：经证实为囊性增生的更年期出血、月经周期不规律、子宫肌瘤伴月经过多、围绝经期激素替代治疗、子宫腺肌病。该制剂记录的效果非常好，副作用很少（7.5%）。作者的结论是，诺古鲁特非常适合在日常妇科实践中用于治疗功能失调性子宫出血、月经周期不规律、更年期激素替代治疗以及减轻子宫腺肌病的症状。
