Sarles H, Gerolami A, Bord A
Digestion. 1978;17(2):128-34. doi: 10.1159/000198103.
In a first study, a population of 1,045 women from 20 to 61 years old has been studies. 24 (2.3%) were known to have gallstones. After excluding these 24 cases, 214 were drawn from the same population and accepted an oral cholecystography. 11 cases of stones (5.1%) were discovered. The diet of these 11 patients and of the 202 women without gallstones was not significantly different. In a second study, the diet of 50 patients with known gallstones and the diet of 50 matched controls have been compared. No significant difference between the two groups can be demonstrated for calories, protein, fat or carbohydrates intake. These results are compared to previous results which showed overconsumption of food in gallstone patients. The method for all studies being similiar, it seems that the dietetic factors are now less important in cholesterol stones pathogenesis than during the period which followed the second world war starvation in southeast France. The assumption that undernutrition diminishes the chance for a women to develop gallstones is proposed.
在第一项研究中，对1045名年龄在20至61岁之间的女性进行了研究。已知有24人（2.3%）患有胆结石。排除这24例病例后，从同一人群中抽取214人接受口服胆囊造影。发现了11例结石病例（5.1%）。这11名患者与202名无胆结石女性的饮食没有显著差异。在第二项研究中，比较了50名已知患有胆结石患者的饮食与50名匹配对照者的饮食。两组在热量、蛋白质、脂肪或碳水化合物摄入量方面没有显著差异。这些结果与之前显示胆结石患者食物摄入过量的结果进行了比较。由于所有研究的方法相似，似乎饮食因素在胆固醇结石发病机制中现在不如第二次世界大战后法国东南部饥荒时期那么重要。有人提出营养不足会降低女性患胆结石几率的假设。
