Wallace H M, Keir H M
J Gen Virol. 1981 Oct;56(Pt 2):251-8. doi: 10.1099/0022-1317-56-2-251.
Confluent monolayers of BHK-21/C13 cells excreted increasing amounts of polyamines into the extracellular medium with time. Excretion was specificity of spermidine and was not the result of cell death or lysis. Herpes simplex virus type 1 (HSV-1) completely prevented excretion of polyamines from 2 h after infection of the cells. The virus specificity inhibited the release of free spermidine but not of conjugated polyamines.
随着时间的推移，汇合的BHK - 21/C13细胞单层向细胞外培养基中分泌的多胺量不断增加。这种分泌具有亚精胺特异性，并非细胞死亡或裂解的结果。单纯疱疹病毒1型（HSV - 1）在感染细胞2小时后完全阻止了多胺的分泌。病毒特异性抑制了游离亚精胺的释放，但不影响结合多胺的释放。
