Gudnadóttir M
Med Biol. 1981 Apr;59(2):77-84.
Sigurdsson's three criterions for a slow viral infection are quoted and discussed and the background of his work briefly described. A fourth criterion for a slow viral infection, is suggested, infection of the hosts lymphoid tissues, which is a common feature of slow infections that have been observed. The general properties of the maedi-visna virus, the diseases and the immune response it causes are discussed. Sheep and goats are susceptible to natural maedi-visna infection. In the goat an identical retrovirus causes arthritis. Arthritis has not been found in maedi-visna infected sheep. Two subacute spongiform encephalopathies of animals are shortly reviewed, scrapie in sheep and goats and transmissible mink encephalopathy (TME). General properties of the very unusual scrapie agent are mentioned briefly. The third type of a slow viral infection is mentioned, Aleutian mink disease, an immunopathological disorder of certain minks caused by a selective infection of lymphoid cells.
引用并讨论了西格德松关于慢病毒感染的三条标准，并简要描述了他的研究背景。提出了慢病毒感染的第四条标准，即宿主淋巴组织感染，这是已观察到的慢感染的一个共同特征。讨论了梅迪-维斯纳病毒的一般特性、它所引起的疾病以及免疫反应。绵羊和山羊易受自然感染梅迪-维斯纳病毒。在山羊中，一种相同的逆转录病毒会导致关节炎。在感染梅迪-维斯纳病毒的绵羊中未发现关节炎。简要回顾了两种动物的亚急性海绵状脑病，绵羊和山羊的羊瘙痒病以及传染性水貂脑病（TME）。简要提及了非常特殊的羊瘙痒病病原体的一般特性。提到了第三种慢病毒感染类型，阿留申水貂病，一种由淋巴细胞选择性感染引起的某些水貂的免疫病理紊乱。
