Tumori. 1981 Aug;67(4):253-72. doi: 10.1177/030089168106700401.
The WHO Histological classification of Lung Tumours, published in 1967, has been revised. The main features are as follows: Squamous cell carcinoma (epidermoid carcinoma) has the same definition as in the original version, i.e., the identification of keratin and/or intercellular bridges by light microscopy. Three degrees of histological differentiation are described. Dysplasia and carcinoma in situ are discussed. Small cell carcinoma is divided into oat-cell carcinoma, an intermediate cell type and a category for oat-cell carcinomas combined with other major types. Adenocarcinoma includes the acinar, papillary and bronchiolo-alveolar forms and the solid carcinomas with mucus formation (previously part of the large cell carcinoma group). Mesothelial tumours are divided into fibrous, epithelial and biphasic subtypes. A number of less common tumours and tumour-like lesions are defined.
1967年出版的世界卫生组织《肺肿瘤组织学分类》已修订。主要特点如下：鳞状细胞癌（表皮样癌）的定义与原版相同，即通过光学显微镜鉴定角蛋白和/或细胞间桥。描述了三种组织学分化程度。讨论了发育异常和原位癌。小细胞癌分为燕麦细胞癌、中间细胞型以及燕麦细胞癌与其他主要类型合并的类别。腺癌包括腺泡状、乳头状和细支气管肺泡型以及有黏液形成的实体癌（以前属于大细胞癌组的一部分）。间皮肿瘤分为纤维型、上皮型和双相亚型。定义了一些不太常见的肿瘤和肿瘤样病变。
