Topuriia I V
Arkh Patol. 1981;43(11):57-63.
The ultrastructural analysis of 40 cases of mammary carcinomas revealed two groups of cells: with ultrastructural organ specific features (differentiated cells) and without them (undifferentiated cells). Intracytoplasmic lumens, secretory granules (lipid, protein, and mixed lipid-protein), and myoepithelial cells are the main organ specific features of mammary carcinomas. The histospecific features showing the epithelial origin of the tumor cells include cell-to-cell contacts, ductules, intercytoplasmic lumens with microvilli, and fragments of basal lamina. These ultrastructural features of mammary carcinomas can facilitate the differential diagnosis of tumors of this organ.
对40例乳腺癌进行的超微结构分析显示出两类细胞：具有超微结构器官特异性特征的（分化细胞）和不具有这些特征的（未分化细胞）。胞质内管腔、分泌颗粒（脂质、蛋白质以及脂质 - 蛋白质混合颗粒）和肌上皮细胞是乳腺癌的主要器官特异性特征。显示肿瘤细胞上皮起源的组织特异性特征包括细胞间连接、小导管、带有微绒毛的胞质间管腔以及基膜碎片。乳腺癌的这些超微结构特征有助于该器官肿瘤的鉴别诊断。
