使用单纯疱疹性角膜炎动物模型对亚单位疫苗进行研究。
Investigation of a sub-unit vaccine using an animal model of herpes simplex keratitis.
作者信息
Harney B A, Easty D L, Skinner G R
出版信息
Trans Ophthalmol Soc U K (1962). 1983;103 ( Pt 3):342-6.
PMID:6324419
Abstract
A rabbit and a mouse model of herpes simplex eye disease have been used to evaluate a sub-unit herpes simplex vaccine. Various immunization schedules were investigated. The vaccine was found to stimulate humoral and cellular immune responses and to offer protection against corneal infection with liver herpes simplex virus.
摘要
一种单纯疱疹眼病的兔和小鼠模型已被用于评估一种亚单位单纯疱疹疫苗。研究了各种免疫方案。发现该疫苗能刺激体液免疫和细胞免疫反应，并能预防单纯疱疹病毒对角膜的感染。
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