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衰老大鼠心房心肌的超微结构变化

Ultrastructural changes in atrial myocardium of the ageing rat.

作者信息

Feldman M L, Navaratnam V

出版信息

J Anat. 1981 Aug;133(Pt 1):7-17.

PMID:6274833
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1167721/
Abstract

Ageing changes in the fine structure of atrial myocardial cells were studied in rats ranging from 2-32 months in age. The most striking change observed was the increasingly frequent appearance, from about 6 months onwards, of helically aggregated strands containing filaments which in respects other than arrangement bore resemblance to thick myofilaments. Other ageing changes included the accumulation of dense bodies and various types of mitochondrial degradation.

摘要

研究了2至32月龄大鼠心房肌细胞精细结构的衰老变化。观察到的最显著变化是,从大约6个月起,含有细丝的螺旋状聚集束越来越频繁地出现,这些细丝除排列方式外,在其他方面与粗肌丝相似。其他衰老变化包括致密体的积累和各种类型的线粒体降解。

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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b31e/1167721/6dea2e400c10/janat00221-0019-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b31e/1167721/a2145fbe91a0/janat00221-0019-b.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b31e/1167721/c76f1bd560ea/janat00221-0019-d.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b31e/1167721/bb6c939b9ddb/janat00221-0020-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b31e/1167721/56ae4306aa50/janat00221-0020-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b31e/1167721/a0ebb9449bcd/janat00221-0020-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b31e/1167721/485974371a21/janat00221-0023-a.jpg
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衰老相关的心肌线粒体超微结构变化出现延迟,是裸鼹鼠()具有返祖特征之一。
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